MEMBERS
Nano Bio Conversion Laboratory
Nano Bio Conversion Laboratory
Professor
Nano Bio Conversion Laboratory (NBCL)
Department of Mechanical & System Design Engineering
College of Engineering
Hongik University
94, Wausan-ro, Mapo-gu, Seoul, Republic of Korea, Hongik University
+82-2-320-1629
Education
Ph.D. in Biomedical Engineering, University of Michigan, Ann Arbor (2008)
MS in Mechanical & Aerospace Engineering, Seoul National University (2003)
BS in Mechanical Engineering, Korea University (2001)
Career
Research Fellow, BioMEMS Resource Center, Center for Engineering in Medicine, Harvard Medical School, Massachusetts General Hospital, USA (2008–2012)
Assistant Professor, Biomedical Engineering, School of Medicine, Keimyung University (2012–2019)
Associate Professor, Biomedical Engineering, College of Engineering & Premedicine, School of Medicine, Keimyung University (2019–2024)
Associate Professor, Department of Mechanical and System Design Engineering, College of Engineering, Hongik University (2024–Present)
Board Member, The Korean Society of Visualization (2014–Present)
Participant Researcher, Medical Research Center (MRC) Program, Ministry of Science, ICT and Future Planning (2014–2021)
Technical Program Committee Member, The International Industrial Information Systems Conference (2014)
Board Member, Bioengineering Division, The Korean Society of Mechanical Engineers (2015–Present)
Board Member, Fluid Engineering Division, The Korean Society of Mechanical Engineers (2016–Present)
Board Member, The Korean BioChip Society (2016–Present)
Expert Member, Next Generation Medical Device 100 Project, Ministry of Food and Drug Safety, Republic of Korea (2016–2018)
Council Member, The Korean Society of Medical & Biological Engineering (2019–Present)
Expert Member, In Vitro Diagnostic Medical Device Expert Committee, Ministry of Food and Drug Safety, Republic of Korea (2020–2022)
Board Member, Institutional Review Board, Kumoh National Institute of Technology (2020–Present)
Vice Editor, Transactions of the Korean Society of Mechanical Engineers B (2021–Present)
Principal Investigator, Basic Research Laboratory (BRL), Ministry of Science and ICT (2021–2024)
Expert Member, Medical Device Committee, Ministry of Food and Drug Safety, Republic of Korea (2021–2024)
Director of Education Operations, IT Medical Convergence Regional Innovation Project (RIS) (2022–2024)
Member, BioHealth Talent Training Council, Ministry of Health and Welfare, Republic of Korea (2023)
Awards
㈜ Selection of Science to Business for Inocube Hosted Contest (2023)
Keimyung University Award for Industry-Academic Research Fellowship (2022)
Minister of Science and ICT Award (2019)
Outstanding Paper Award in the Society of Medical Bioengineering (2019)
Korea Society of Visualization Award for Achievement (2019)
Korea Society of Visualization Award for Achievement (2019)
Osaka University Bioengineering Colloquium testimonial (2019)
Emerging Technologies in Mechanical Engineering (ETME) 2018 Best Paper Award (2018)
Keimyung University Award for Industry-Academic Research Fellowship (2017)
Korean Society of Visualized Information Award (2016)
(사) The Korean Society of Molecular Cell Biology Outstanding Poster Award (2015)
SIC Colloquium testimonial at Gwangju Institute of Science and Technology (2013)
MICROTAS 2009 Travel Grant award (2009)
SART Prize (Best paper award) at 2008 American Society for Reproductive Medicine (ASRM) Annual meeting (San Francisco, CA) (2008)
Best Speaker Award, Microfluidics in Biomedical Sciences Seminar Series, University of Michigan (2008)
Graduate Student Research Assistantship, University of Michigan (2004~2008)
LabAutomation2006 (Palm Springs, CA, 2006) Academic Grant winner (award), ALA(Association for Laboratory Automation) (2006)
LabAutomation2005 (San Jose, CA, 2005) Academic Grant winner (award), ALA(Association for Laboratory Automation) (2005)
Biomedical engineering fellowship Award (University of Michigan) (2003~2004)
The Graduate Studies Abroad Program award ($60,000), Korea Science and Engineering Foundation (KOSEF) (2003~2005)
Research assistantship, Digital Bio Technology co. (2002~2003)
Research assistantship, Brain Korea 21 in Seoul National University. (2001~2002)
Tuition scholarships : 1st,2nd Semester 1 in Seoul National University. (2001)
First Class Honors for 1stand 2nd Semester in Korea University (2000)
Honors Scholarships in Korea University (2000)
First Class Honors (Award) for 2nd Semester in Korea University (1999)
Study Scholarships in Korea University (1997~1998)
Honors Scholarships in Korea University (1996)
Book
Heo, Y. S., Jovic, A., Carbrera, L.M., Smith, G. D., Takayama, S. “Osmolality control for microfluidic embryo cell culture using hybrid polydimethylsiloxane (PDMS)-Parylene membrances” Methods in Bioengineering, Microdevices in biology and medicine. 2009, 109-127. (Book Chapter)
Medical Device Design and Introduction, Heo, Y.S., (ISBN: 978-89-7585-663-1)
Introduction to Medical Imaging, Heo, Y.S. et al, Hantee Media, (ISBN 978-89-6421-329-2)
Foreign Invited Talks
Invited Speaker, "Single Embryo Culture and Assay System for the In Vitro Fertilization (IVF) Technology," Wayne State University Seminar and Training & Collaboration Workshop, USA. (Feb 14, 2024)
Invited Speaker, "Single embryo culture and assay systems for in vitro fertilization (IVF)," China-Japan-Korea Forum on "Bionic Engineering and Modern Agriculture Development," Jilin University, China. (Nov 05, 2022)
Invited Speaker, "Optimized Culture and Assay Systems for the In Vitro Fertilization (IVF) Technologies," The 18th International Symposium of MEI Center, Osaka University, Japan. (Aug 06, 2021)
Invited Speaker, "Microfluidic Application for Assisted Reproductive Technology (ART)," Jilin University and KSME BioEngineering Division Joint Workshop, Jilin University, China. (Sep 20, 2019)
Keynote Speaker, "Microfluidic Application for Assisted Reproductive Technology (ART)," Bio-Colloquium at Osaka University, Japan. (Jul 12, 2019)
Domestic Invited Talks
Invited Speaker, "Single Embryo Culture and Diagnostic Systems and Biosensor Technology Applications for Overcoming Low Birth Rate and Improving Technical Aspects of In Vitro Fertilization," The 112th Organ-on-a-Chip Technology Exchange Meeting, Hallym University, South Korea. (Nov 28, 2024)
Invited Speaker, "Label-free electrochemical biosensor for glycated hemoglobin (HbA1c) and glycated albumin (GA) measurement using (chemical affinity binding / 4-mercapto-phenyl boronic acid embedded affinity)," 2024 Symposium on New Drugs and Technology Development for Metabolic Diseases, Korean Diabetes Association, South Korea. (Sep 27, 2024)
Invited Speaker, "Label-free electrochemical detection of glucose and glycated hemoglobin (HbA1c)," Symposium of the Study Group for New Drugs and Technology Development for Metabolic Diseases, Korean Diabetes Association, South Korea. (Sep 15, 2023)
Invited Speaker, "Single Embryo Culture and Assay System for the In Vitro Fertilization (IVF) Technologies," Spring Conference of the Korean BioChip Society, South Korea. (Jun 01, 2023)
Invited Speaker, "Biosensors for Measuring Metabolic Disease Biomarkers," Symposium of the Study Group for New Drugs and Technology Development for Metabolic Diseases, Korean Diabetes Association, South Korea. (Oct 21, 2022)
Invited Speaker, "Self-diagnostic Markers and In-vitro Diagnostic Devices for Managing Adult Diseases (Obesity, Diabetes, and Diabetic Complications) in the Contactless Era," 2nd Science and Technology Development Strategy Forum, KOFST, South Korea. (Aug 10, 2022)
Invited Speaker, "Biosensors for Measuring Metabolic Disease Biomarkers," Seminar of the Study Group for New Drugs and Technology Development for Metabolic Diseases, Korean Diabetes Association, South Korea. (Feb 04, 2022)
Invited Speaker, "Diagnosis of Obesity and Biomarkers," Workshop of the Metabolic Obesity and Nutrition Study Group, Korean College of Helicobacter and Upper Gastrointestinal Research, South Korea. (Jan 09, 2022)
Invited Speaker, "The Path Forward for Engineering and Medicine Together," Dongsan Medical Center Research EXPO, Keimyung University Dongsan Medical Center, South Korea. (Dec 08, 2021)
Invited Speaker, "Development of Diagnostic Systems and Platforms for Diabetic Complication Biomarkers," Invited Lecture for Research-Driven Hospital R&D Project, Yonsei University Severance Hospital, South Korea. (Jun 04, 2021)
Invited Speaker, "What is Biomedical Engineering?," Special Invited Lecture, Daejin High School, South Korea. (May 11, 2021)
Invited Speaker, "Microfluidic applications for ART," 77th Autumn Meeting of the Korean Society for Reproductive Medicine, South Korea. (Nov 16, 2019)
Invited Speaker, "Medicine and Engineering: Finding the Interface with a Human-Centric Approach - Progress and Achievements in Medical Device Development," 13th Museum Culture College Invited Lecture, Chuncheon National Museum, South Korea. (Jul 12, 2018)
Invited Speaker, "Microfluidics for Assisted Reproductive Technology (ART)," Fluids Engineering Division Conference of the Korean Society of Mechanical Engineers (KSME), South Korea. (May 26, 2017)
Invited Speaker, "Microfluidic Applications in the Field of Assisted Reproductive Technology," 2017 Spring Meeting of the Korean Society of Industrial and Engineering Chemistry (KSIEC), South Korea. (May 11, 2017)
Invited Speaker, "Bioinspired Microfluidic and Microcapillary systems for biomedical applications," SIC Colloquium, School of Information and Communications, Gwangju Institute of Science and Technology (GIST), South Korea. (Apr 26, 2013)
Implemented research project
Principal Investigator, "Embryo Dynamic Culture and Embryo Quality Assessment Systems for Controlling Embryo Development and Improving Implantation Efficiency," Ministry of Science and ICT (MSIT), Basic Research Program. (Jun 2023 – Feb 2026)
Principal Investigator, "Basic Research Lab (BRL) for Soundwave Control-based Single Embryo Characterization," Ministry of Science and ICT (MSIT). (Jun 2021 – Feb 2024)
Co-Investigator, "Development of a Prediction Model for Diabetes and Diabetic Complication Progression Based on a Multi-diagnostic Chip," Ministry of Health and Welfare (MOHW), Research-Driven Hospital R&D Project. (Jul 2018 – Dec 2026)
Principal Investigator, "Integrated Fluidic System for Reproductive Cell Co-culture Utilizing Fluid Characteristic-based Micro-patterning and Particle Separation for Overcoming Infertility," Ministry of Science and ICT (MSIT), Basic Research Program. (Jun 2020 – Feb 2023)
Co-Principal Investigator, "Advanced Measurement Technology and Clinical Application for the Commercialization of Portable Insulin Resistance Diagnostic Devices," Ministry of Science and ICT (MSIT) / INNOPOLIS Foundation. (Sep 2020 – Aug 2031)
Principal Investigator, "Sensitivity Enhancement of Insulin Resistance Diagnostic Sensors Using Nano-structured Electrodes," Ministry of Science and ICT (MSIT) / INNOPOLIS Foundation. (Apr 2018 – Dec 2019)
Principal Investigator, "Oviduct-mimicking Microfluidic System for Early Embryo Generation Models," Ministry of Science and ICT (MSIT), Mid-career Research Program. (Mar 2017 – Feb 2020)
Co-Investigator, "Obesity-mediated Disease Research Center," Ministry of Science and ICT (MSIT), Medical Research Center (MRC) Program. (May 2014 – Feb 2020)
Co-Principal Investigator, "Development of Portable Insulin Resistance Diagnostic Devices for Early Diagnosis and Prevention of Diabetes," Ministry of Science and ICT (MSIT) / INNOPOLIS Foundation. (May 2019 – May 2020)
Co-Principal Investigator, "Development of Impression Material-saving Mixing Tips with Improved Compression Efficiency Using Fixed and Rotary Wing Hybrid Mixing," Ministry of Science and ICT (MSIT) / INNOPOLIS Foundation. (Apr 2016 – Apr 2018)
Principal Investigator, "Development of Static Mixers for Impression Material Mixing," Ministry of Education (MOE) / National Research Foundation (NRF). (Jun 2016 – Jan 2017)
Principal Investigator, "Technological Advancement in Assisted Reproductive Technology (ART) via Development of Embryo Cryopreservation, Biomimetic Culture, and Diagnostic Systems," Ministry of Education (MOE) / National Research Foundation (NRF), Basic Research Program. (Nov 2014 – Apr 2017)
Principal Investigator, "Development of Micro-connection Modules for Diagnostic Medical Devices," Ministry of Education (MOE) / National Research Foundation (NRF). (Jun 2015 – Dec 2015)
Research Participant, "Development and Commercialization Support for Arrhythmia Diagnostic and Therapeutic Devices," Ministry of Trade, Industry and Energy (MOTIE) / Korea Institute for Advancement of Technology (KIAT). (Aug 2013 – Apr 2015)
Research Participant, "Development of Smart Steering Wheels for Driver State Detection Based on Biosignal Recognition," Ministry of Knowledge Economy (MKE). (Apr 2013 – Jul 2015)
Principal Investigator, "Development of Core Component Modules (Polymer Microcapillaries) for Medical Cell Rapid Freezing Devices," Ministry of Education (MOE) / National Research Foundation (NRF). (Jun 2013 – Jan 2014)
Brands
Lead Inventor, "Class 10 Medical Cell Culture Apparatus, etc. (9 items)," Republic of Korea, Reg. No. 40-1983661. (Mar 02, 2023)
Lead Inventor, "Class 42 Scientific Research/Survey in the Field of Biomedicine, etc. (9 items)," Republic of Korea, Reg. No. 40-1983666. (Mar 02, 2023)
Lead Inventor, "HOMACHIP," Republic of Korea, Reg. No. 40-1138056. (Oct 22, 2015)